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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
The top drug-food interactions for

Disclaimer:

There are additional precautions and alternative ways to reduce your risk of experiencing drug-food interactions. Please seek advice from your healthcare provider or pharmacist before taking any new interactions.

Also, if you have any underlying health conditions, including:
  • Hepatitis B
  • High blood pressure
  • Menstruation problems
  • Proteinolesterol

You should not take Cialis or other ED medications if you are taking alpha-blockers like Pravastatin or Verapamil, as the combination can cause serious heart problems or stroke in those who have a history of these medications. Furthermore, Cialis can also cause low blood pressure when taken with other drugs taken with alpha-blockers.

For more information, please read the

ichever field is your healthcare provider's area of expertise or you have any questions or concerns about ED medications, they are available atView more about.

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

Cameron, S. W. demonstrated that PDE5 inhibitors significantly improved erectile dysfunction in rats. Findings showed that PDE5 inhibitors significantly improved erectile dysfunction in rats. Findings showed that PDE5 inhibitors significantly enhanced pulmonary hypertension. PDE5 inhibitors significantly enhanced pulmonary hypertension. PDE5 inhibitors also significantly increased risk of cardiovascular events including heart attack, heart failure, and stroke.”

This medication is not advised for people with a recent history of priapism. priapism is a medical emergency. If you experience chest pain, shortness of breath, or pain along with this side effect, call your doctor immediately or go to the emergency room. Do not take PDE5 inhibitors if you are allergic to it or used nitrates to treat angina or have had a recent priapism attack. Do not take PDE5 inhibitors if you are taking cilostazol ( Alessio Gramsci.”

If you experience chest pain, shortness of breath, or pain with this medication, call a doctor or get emergency medical treatment immediately. Do not take PDE5 inhibitors if you are taking riociguat (Adempas.”

Do not take PDE5 inhibitors if you are taking riociguat (Adempas.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information online andoyndeckmann-disag- Salam language Salam ( UK licensed medicine on VOA market, which is owned by Dr Fox ) Palpitations and syncopia (light heartbeats and slow fainting) - Do not breathe as i am notesyb Candidate technician: Black, male, no previous drug interactions patch/diabetic, thyroid, lung disease, high blood pressure, kidney disease, stomach ulcer, high cholesterol, smoke, drink alcohol, have heart disease, are breastfeeding, smoke, have recently had a heart attack or stroke, are>[ ] have ever had a heart attack, stroke or unstable angina? FAQ: What if Tadalafil is right for you? Yes, take Tadalafil once a day. However, if you have had a heart attack or stroke in the last 6 months you should take no more than 2 medications together. No more than 3 medications together. No more than 4 medications together. No more than 5 medications together. No more than 6 medications together. No more than 7 medications with other medications in the same medicine class. No more than 8 medications with other medications in the same medicine class. No more than 9 medications with other medications in the same medicine class. No more than 10 medications with other medications in the same medicine class. No more than 11 medications with other medications in the same medicine class. No more than 12 medications with other medications in the same medicine class. No more than 15 medications with other medications in the same medicine class. No more than 20 medications with other medications in the same medicine class. No more than 30 medications with other medications in the same medicine class.

If you don’t know what the problem is, you’re not alone. There are many causes of erectile dysfunction, including stress and anxiety. That’s why the first thing you should do is try to avoid taking the medication. The main drug in the market, sildenafil, has been proven to help with erections, even in healthy men. But it’s important to know that the effects of the drug are not permanent and they’re not guaranteed to be effective. To make sure you take the right medication for your body, it’s important to take it every day.

The best part of all these medications is that they are safe, but if you are not healthy enough to take them, you may not be able to get an erection, which is why the best option to try is to go for a lower dose of the medication. This is because the medication has been shown to affect the production of nitric oxide, which is responsible for relaxing the muscles in the penis. This helps the blood vessels that supply blood to the penis to relax and increase blood flow. When the blood flow to the penis increases, the muscles in the penis will get bigger and larger. This is why it’s important to take the medication at the same time every day.

How To Take Tadalafil?

Tadalafil is a medication that comes in two types of pills: the one that is manufactured by Pfizer and the one that is available as an oral tablet. There are two different types of tadalafil, one is the branded version, and the other is the generic version. Both of these medications are available in the same dosage that comes in the pack. They work in the same way, but they have a different effect. It’s important to note that there are different dosages available for each type of drug. It is important to consult with a doctor or healthcare professional to determine the ideal dosage for each of these medications.

It is important to take the drug at the same time each day. This means that taking it at the same time every day will help you to get an erection for the best results. The medication can be taken up to a maximum of 10 hours before intercourse. This allows for the medication to be absorbed more quickly. The medication will start working and will not stop working overnight. The best thing about this medication is that it will work faster and stay active for longer.

Side Effects Of Tadalafil

Like all medications, tadalafil may cause side effects. The side effects are generally mild and tend to improve as your body adjusts to the medication. However, they are still important for some people. These side effects can be mild and temporary. They can be caused by the medication, but they are also possible if you take other medications. These other medications are also known as PDE5 inhibitors, which are medications that have been used to help treat erectile dysfunction.

Cialis Together for Erectile Dysfunction

Cialis Together tablets are a treatment for adult men who have erection problems (erectile dysfunction). This is when a man cannot get, or keep an erection hard enough for satisfactory sexual activity.

Cialis Together tablets contain the active substance tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood flow into your penis.

It is important to know that you will not get an erection just by taking Cialis Together tablets. This medicine works with your body’s natural function to get an erection only when you are sexually stimulated.

Cialis Together contains the active ingredient Tadalafil. The ingredient is a phosphodiesterase type 5 inhibitor medicine that temporarily improves blood flow to the penis by relaxing the blood vessels in and around the area.

The Cialis Together medication is available over-the-counter and begins to work about 30 to 60 minutes after taking it. The effects are expected to last up to 36 hours. Cialis Together comes in 10mg tablets and should only be taken when needed.

The active substance Tadalafil is also useful in treating other conditions along with erectile dysfunction. Please consult a Doctor, a Pharmacist or relevant product literature for more information.

Is Cialis Together right for me?

If you suffer from erectile dysfunction (impotence) Cialis Together may be an effective treatment. However, it may not be suitable for you if you have the following:

  • If you are allergic to any of the ingredients in Cialis Together
  • If you have severe heart, liver or kidney problems
  • If you have blood pressure concerns
  • If you have non-arteritic anterior ischemic optic neuropathy
  • If you are taking riociguat
  • If you have other penis-related issues (deformation or painful erections)
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